MARCHF6

Across TCGA patient cohorts, MARCHF6 protein abundance is significantly associated with the protein abundance of many other proteins, with 7,261 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MARCHF6-associated proteins across cancer lineages are ATP2A2, SMPD4, and SRPRB. Each is linked with MARCHF6 in more than 4 cancer types. Because this analysis shows association rather than direction, both MARCHF6-to-partner and partner-to-MARCHF6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MARCHF6 versus ATP2A2 in BRCA, with a Pearson correlation of 0.68.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MARCHF6→partner) and Y-score (partner→MARCHF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ATP2A2 →	+0.690	+0.577	<.001	<.001	3	5
BRCA	SMPD4 →	+0.460	+0.617	<.001	<.001	3	4
BRCA	SRPRB →	+0.616	+0.489	<.001	<.001	3	4
BRCA	MTCH1 →	+0.408	+0.324	<.001	.002	2	5
BRCA	LMBRD2 →	+0.471	+0.379	<.001	<.001	3	4
BRCA	HACD2 →	+1.014	+0.481	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,261 associations by consensus.

MARCHF6 vs ATP2A2 — BRCA

Explore this scatter interactively →