MARCHF6

Across TCGA cell cohorts, MARCHF6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,950 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MARCHF6-associated GO terms across cancer lineages are Establishment of RNA localization, Regulation of syncytium formation by plasma membrane fusion, and Protein localization to vacuole. Each is linked with MARCHF6 in more than 14 cancer types. Because this analysis shows association rather than direction, both MARCHF6-to-partner and partner-to-MARCHF6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of RNA localization grouped by MARCHF6-low versus MARCHF6-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MARCHF6→partner) and Y-score (partner→MARCHF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Establishment of RNA localization →	+0.125	+1.541	<.001	<.001	3	14
STOMACH	Regulation of syncytium formation by plasma membrane fusion →	+0.139	+1.143	<.001	<.001	3	14
STOMACH	Protein localization to vacuole →	+0.065	+0.699	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.060	+1.079	.005	.003	3	14
BONE	Post-transcriptional gene silencing →	+0.099	+0.923	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.137	+1.234	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,950 associations by consensus.

Establishment of RNA localization by MARCHF6 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →