MARCHF6

Across TCGA cell cohorts, MARCHF6 mutation is significantly associated with the drug of many other genes, with 26 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MARCHF6-associated genes across cancer lineages are UNC0642, AZD1208, and PRT062607. Each is linked with MARCHF6 in more than 1 cancer types. Because this analysis shows association rather than direction, both MARCHF6-to-partner and partner-to-MARCHF6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UNC0642 grouped by MARCHF6-low versus MARCHF6-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MARCHF6→partner) and Y-score (partner→MARCHF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	UNC0642 →	+0.187	+2.658	.047	.043	3	1
LARGE_INTESTINE	AZD1208 →	+0.349	+2.649	.044	.046	3	1
LARGE_INTESTINE	PRT062607 →	+0.516	+2.769	.042	.040	3	1
LARGE_INTESTINE	PAK_5339 →	+0.410	+2.678	.005	.037	3	1
LARGE_INTESTINE	630600 →	+0.689	+2.649	.026	.046	3	1
LARGE_INTESTINE	KIN001-236 →	+0.294	+2.652	.041	.045	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

UNC0642 by MARCHF6 expression — LARGE_INTESTINE

Explore this box plot interactively →