Across TCGA patient cohorts, MARCHF5 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,652 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MARCHF5-associated proteins across cancer lineages are NHLRC2, HDAC2, and EVL_S246. Each is linked with MARCHF5 in more than 4 cancer types. Because this analysis shows association rather than direction, both MARCHF5-to-partner and partner-to-MARCHF5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MARCHF5→partner) and Y-score (partner→MARCHF5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	NHLRC2 →	+0.231	+0.387	.002	.006	3	5
GBM	HDAC2 →	+0.367	+0.329	.001	.005	3	5
UCEC	EVL_S246 →	-0.709	-0.327	<.001	.007	3	5
OV	BTAF1 →	+0.254	+0.478	<.001	<.001	3	5
GBM	RACK1 →	-0.159	-0.293	.001	.002	3	4
LSCC	PES1 →	+0.387	+0.385	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,652 associations by consensus.

Exploration

MARCHF5 survival (RNA) · tumor vs normal (RNA) · all MARCHF5 data types