MARCHF4

Across TCGA cell cohorts, MARCHF4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,453 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MARCHF4-associated GO terms across cancer lineages are PML body organization, Regulation of fibrinolysis, and Dentinogenesis. Each is linked with MARCHF4 in more than 13 cancer types. Because this analysis shows association rather than direction, both MARCHF4-to-partner and partner-to-MARCHF4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PML body organization grouped by MARCHF4-low versus MARCHF4-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MARCHF4→partner) and Y-score (partner→MARCHF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	PML body organization →	+0.212	+2.549	<.001	<.001	3	14
BONE	Regulation of fibrinolysis →	+0.410	+1.938	<.001	.001	3	14
BONE	Dentinogenesis →	+1.867	+1.891	<.001	<.001	3	14
LIVER	Positive regulation of establishment of T cell polarity →	+0.220	+2.291	<.001	<.001	3	13
LIVER	Positive regulation of natural killer cell differentiation →	+0.750	+2.124	.002	.001	3	13
URINARY_TRACT	Positive regulation of dopamine uptake involved in synaptic transmission →	+1.388	+2.680	<.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,453 associations by consensus.

PML body organization by MARCHF4 expression — BONE

Explore this box plot interactively →