MARCHF3

Across TCGA patient cohorts, MARCHF3 protein abundance is significantly associated with the RNA expression of many other genes, with 388 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MARCHF3-associated genes across cancer lineages are MYH9, COL20A1, and ELF4. Each is linked with MARCHF3 in more than 1 cancer types. Because this analysis shows association rather than direction, both MARCHF3-to-partner and partner-to-MARCHF3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MARCHF3 versus MYH9 in GBM, with a Pearson correlation of -0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MARCHF3→partner) and Y-score (partner→MARCHF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MYH9 →	-0.910	-0.677	.002	.001	3	1
GBM	COL20A1 →	+3.423	+0.615	<.001	.005	3	1
GBM	ELF4 →	-1.045	-0.677	.004	.001	3	1
GBM	CD276 →	-0.854	-0.848	.004	.002	3	1
GBM	GDAP1 →	+1.070	+0.713	.001	.002	3	1
GBM	GFUS →	-0.366	-0.608	.004	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 388 associations by consensus.

MARCHF3 vs MYH9 — GBM

Explore this scatter interactively →