MARCHF10

Across TCGA cell cohorts, MARCHF10 mutation is significantly associated with the RNA expression of many other genes, with 113 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MARCHF10-associated genes across cancer lineages are MMP26, TEX53, and CRX. Each is linked with MARCHF10 in more than 1 cancer types. Because this analysis shows association rather than direction, both MARCHF10-to-partner and partner-to-MARCHF10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MMP26 grouped by MARCHF10-low versus MARCHF10-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MARCHF10→partner) and Y-score (partner→MARCHF10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	MMP26 →	+0.026	+4.807	<.001	.006	3	2
LUNG_NSCLC_LUAD	TEX53 →	+0.106	+4.371	<.001	.005	3	2
SKIN	CRX →	+0.004	+3.345	<.001	.007	3	1
SKIN	PSKH2 →	+0.021	+3.632	<.001	.003	3	1
SKIN	OR10AG1 →	+0.081	+3.345	<.001	.007	3	1
SKIN	CT83 →	+1.010	+3.453	.006	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 113 associations by consensus.

MMP26 by MARCHF10 expression — BLOOD_Myeloma

Explore this box plot interactively →