MAPRE3

Across TCGA cell cohorts, MAPRE3 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MAPRE3-associated genes across cancer lineages are OR2AJ1 and OR2D3. Each is linked with MAPRE3 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAPRE3-to-partner and partner-to-MAPRE3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2AJ1 grouped by MAPRE3-low versus MAPRE3-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAPRE3→partner) and Y-score (partner→MAPRE3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR2AJ1 →	+0.042	+4.867	<.001	.009	3	1
LARGE_INTESTINE	OR2D3 →	+0.029	+4.510	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR2AJ1 by MAPRE3 expression — BLOOD_Lymphoma

Explore this box plot interactively →