MAPRE2

Across TCGA patient cohorts, MAPRE2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,143 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MAPRE2-associated proteins across cancer lineages are SEPTIN4, MAPRE2_S223, and TLN1. Each is linked with MAPRE2 in more than 5 cancer types. Because this analysis shows association rather than direction, both MAPRE2-to-partner and partner-to-MAPRE2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAPRE2 versus SEPTIN4 in PDAC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MAPRE2→partner) and Y-score (partner→MAPRE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SEPTIN4 →	+0.645	+0.494	<.001	<.001	3	6
CCRCC	MAPRE2_S223 →	+1.583	+1.292	.003	.001	3	6
PDAC	TLN1 →	+0.354	+0.413	<.001	<.001	3	6
OV	TMOD2 →	+0.557	+1.271	<.001	<.001	3	6
OV	ILK →	+0.442	+1.169	<.001	<.001	3	6
HNSC	SORBS1 →	+0.465	+0.373	.003	.007	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,143 associations by consensus.

MAPRE2 vs SEPTIN4 — PDAC

Explore this scatter interactively →