MAPRE2

Across TCGA cell cohorts, MAPRE2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,929 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MAPRE2-associated GO terms across cancer lineages are Protein localization to microtubule, Spindle assembly, and Protein localization to microtubule cytoskeleton. Each is linked with MAPRE2 in more than 14 cancer types. Because this analysis shows association rather than direction, both MAPRE2-to-partner and partner-to-MAPRE2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to microtubule grouped by MAPRE2-low versus MAPRE2-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAPRE2→partner) and Y-score (partner→MAPRE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Protein localization to microtubule →	+0.123	+1.875	.003	.009	3	15
BLOOD_Myeloma	Spindle assembly →	+0.085	+1.142	.002	.009	3	11
OESOPHAGUS	Protein localization to microtubule cytoskeleton →	+0.086	+1.500	.002	.007	3	11
BREAST	Positive regulation of cell-substrate junction organization →	+0.096	+1.525	.006	.004	3	11
BLOOD_Myeloma	Regulation of focal adhesion disassembly →	+0.147	+1.626	<.001	.001	3	10
BONE	Protein localization to cytoskeleton →	+0.056	+0.776	.003	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,929 associations by consensus.

Protein localization to microtubule by MAPRE2 expression — LUNG_NSCLC_LUSC

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