MAPRE1P2

Across TCGA patient cohorts, MAPRE1P2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,177 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MAPRE1P2-associated GO terms across cancer lineages are Negative regulation of telomere maintenance, Protein sumoylation, and RNA 3'-end processing. Each is linked with MAPRE1P2 in more than 20 cancer types. Because this analysis shows association rather than direction, both MAPRE1P2-to-partner and partner-to-MAPRE1P2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of telomere maintenance grouped by MAPRE1P2-low versus MAPRE1P2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAPRE1P2→partner) and Y-score (partner→MAPRE1P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of telomere maintenance →	+0.040	+0.093	<.001	<.001	3	21
STAD	Protein sumoylation →	+0.042	+0.081	<.001	<.001	3	20
STAD	RNA 3'-end processing →	+0.051	+0.099	<.001	<.001	3	20
ESCA	DNA-templated transcription initiation →	+0.069	+0.180	.002	.003	3	20
STAD	Regulation of organelle assembly →	+0.043	+0.109	<.001	<.001	3	20
ESCA	Negative regulation of ubiquitin-dependent protein catabolic process →	+0.062	+0.138	.005	<.001	2	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,177 associations by consensus.

Negative regulation of telomere maintenance by MAPRE1P2 expression — STAD

Explore this box plot interactively →