MAPRE1

Across TCGA patient cohorts, MAPRE1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,131 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MAPRE1-associated genes across cancer lineages are FAM174A, CDK5RAP1, and RAB22A. Each is linked with MAPRE1 in more than 4 cancer types. Because this analysis shows association rather than direction, both MAPRE1-to-partner and partner-to-MAPRE1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAPRE1 versus FAM174A in BRCA, with a Pearson correlation of -0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAPRE1→partner) and Y-score (partner→MAPRE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FAM174A →	-0.442	-0.156	.009	.002	3	5
COAD	CDK5RAP1 →	+0.541	+0.303	<.001	<.001	3	5
GBM	RAB22A →	+0.364	+0.185	.002	.003	3	5
LSCC	PHF20 →	+0.414	+0.255	.001	<.001	3	5
PDAC	FFAR2 →	-0.932	-0.234	<.001	<.001	3	5
LUAD	ASS1 →	-0.671	-0.140	.005	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,131 associations by consensus.

MAPRE1 vs FAM174A — BRCA

Explore this scatter interactively →