MAPRE1

Across TCGA cell cohorts, MAPRE1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,487 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MAPRE1-associated GO terms across cancer lineages are Mitotic nuclear division, Sister chromatid segregation, and Mitotic sister chromatid segregation. Each is linked with MAPRE1 in more than 15 cancer types. Because this analysis shows association rather than direction, both MAPRE1-to-partner and partner-to-MAPRE1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic nuclear division grouped by MAPRE1-low versus MAPRE1-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAPRE1→partner) and Y-score (partner→MAPRE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Mitotic nuclear division →	+0.084	+0.758	<.001	<.001	3	16
CNS	Sister chromatid segregation →	+0.087	+0.701	<.001	<.001	3	16
PANCREAS	Mitotic sister chromatid segregation →	+0.117	+0.980	<.001	<.001	3	16
BREAST	Nuclear chromosome segregation →	+0.088	+0.790	.002	.004	2	16
BREAST	Regulation of chromosome separation →	+0.149	+0.771	.001	.007	3	15
BREAST	Positive regulation of cell cycle checkpoint →	+0.116	+0.741	<.001	.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,487 associations by consensus.

Mitotic nuclear division by MAPRE1 expression — CNS

Explore this box plot interactively →