MAPKAPK3

Across TCGA pan-cancer cohorts, MAPKAPK3 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated MAPKAPK3 data layer compared with 22 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher MAPKAPK3 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated MAPKAPK3 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

COAD, CCRCC, and GBM are the cancer types where MAPKAPK3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	0.899	1.000	.021	42	view →
CCRCC	DFS	Quartile	II,III,IV	0.788	0.393	.009	28	view →
GBM	DFS	Median	All	0.635	0.796	.003	17	view →
PDAC	DFS	Median	II,III,IV	0.645	0.803	.015	8	view →
HNSC	DFS	Median	II,III,IV	0.911	0.978	.032	5	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

MAPKAPK3–COAD (DFS)

Open the COAD breakdown →