MAPKAPK3

Across TCGA patient cohorts, MAPKAPK3 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,168 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible MAPKAPK3-associated proteins across cancer lineages are SLC9A7_S693, ACAA1, and CCDC9B. Each is linked with MAPKAPK3 in more than 3 cancer types. Because this analysis shows association rather than direction, both MAPKAPK3-to-partner and partner-to-MAPKAPK3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAPKAPK3 versus SLC9A7_S693 in PDAC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MAPKAPK3→partner) and Y-score (partner→MAPKAPK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SLC9A7_S693 →	+0.696	+0.292	<.001	.006	3	4
PDAC	ACAA1 →	+0.323	+0.427	.003	<.001	3	4
GBM	CCDC9B →	+0.535	+0.437	.001	<.001	3	4
GBM	TWF2 →	+0.264	+0.448	<.001	<.001	3	4
GBM	ESYT1 →	+0.276	+0.418	.003	<.001	3	4
BRCA	USP4 →	+0.260	+0.457	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,168 associations by consensus.

MAPKAPK3 vs SLC9A7_S693 — PDAC

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