MAPKAPK3

Across TCGA patient cohorts, MAPKAPK3 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAPKAPK3-associated genes across cancer lineages are Adipocytes, Keratinocytes, and Sebocytes. Each is linked with MAPKAPK3 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAPKAPK3-to-partner and partner-to-MAPKAPK3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Adipocytes grouped by MAPKAPK3-low versus MAPKAPK3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAPKAPK3→partner) and Y-score (partner→MAPKAPK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Adipocytes →	+0.023	+2.922	.013	.003	3	1
UCEC	Keratinocytes →	+0.021	+3.048	.004	.018	3	1
UCEC	Sebocytes →	+0.044	+3.032	<.001	.018	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Adipocytes by MAPKAPK3 expression — UCEC

Explore this box plot interactively →