MAPKAPK2

Across TCGA cell cohorts, MAPKAPK2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,433 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MAPKAPK2-associated GO terms across cancer lineages are Endocytic recycling, Response to hypoxia, and Response to epidermal growth factor. Each is linked with MAPKAPK2 in more than 13 cancer types. Because this analysis shows association rather than direction, both MAPKAPK2-to-partner and partner-to-MAPKAPK2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endocytic recycling grouped by MAPKAPK2-low versus MAPKAPK2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAPKAPK2→partner) and Y-score (partner→MAPKAPK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Endocytic recycling →	+0.081	+1.116	.001	<.001	3	14
LIVER	Response to hypoxia →	+0.069	+1.132	.001	<.001	3	13
BONE	Response to epidermal growth factor →	+0.109	+0.948	.005	.001	3	13
BONE	Vesicle-mediated transport to the plasma membrane →	+0.094	+1.326	<.001	<.001	3	13
BONE	Negative regulation of calcineurin-mediated signaling →	+0.207	+0.887	<.001	<.001	3	12
BONE	Positive regulation of epithelial cell migration →	+0.139	+1.258	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,433 associations by consensus.

Endocytic recycling by MAPKAPK2 expression — BONE

Explore this box plot interactively →