MAPK8IP1P1

Across TCGA pan-cancer cohorts, MAPK8IP1P1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated MAPK8IP1P1 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher MAPK8IP1P1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MAPK8IP1P1 expression acts as an unfavorable survival marker, although some lineages such as CESC and HNSC show a favorable association.

KICH, ACC, and CESC are the cancer types where MAPK8IP1P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Quartile	All	0.784	1.000	.001	70	view →
ACC	DFS	Quartile	III,IV	0.105	0.566	<.001	43	view →
CESC	DFS	Median	II,III,IV	0.618	0.362	.002	38	view →
DLBC	DFS	Tertile	III,IV	0.196	0.862	.008	36	view →
READ	DFS	Quartile	All	0.677	0.847	.008	28	view →
HNSC	OS	Median	II,III,IV	0.729	0.466	<.001	27	view →
UVM	DFS	Quartile	All	0.427	0.798	.013	16	view →
THCA	OS	Tertile	II,III,IV	0.632	0.962	.013	15	view →
SKCM	OS	Tertile	IV	0.867	0.267	.008	9	view →
MESO	DFS	Quartile	All	0.679	0.380	.021	9	view →
PAAD	DFS	Quartile	II,III,IV	0.267	0.457	.003	6	view →
KIRC	DFS	Median	IV	0.320	0.573	.038	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

MAPK8IP1P1–KICH (OS)

Open the KICH breakdown →