MAPK8IP1

Across TCGA pan-cancer cohorts, MAPK8IP1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated MAPK8IP1 data layer compared with 25 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher MAPK8IP1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated MAPK8IP1 expression acts as an unfavorable survival marker.

LUAD, LSCC, and GBM are the cancer types where MAPK8IP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	III,IV	0.413	1.000	.010	19	view →
LSCC	OS	Median	II,III,IV	0.460	0.921	.008	6	view →
GBM	OS	Tertile	All	0.384	0.741	.009	5	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

MAPK8IP1–LUAD (OS)

Open the LUAD breakdown →