MAPK7

Across TCGA patient cohorts, MAPK7 mutation is significantly associated with the RNA expression of many other genes, with 1,737 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAPK7-associated genes across cancer lineages are SAR1AP1, IMP3P2, and OR13I1P. Each is linked with MAPK7 in more than 3 cancer types. Because this analysis shows association rather than direction, both MAPK7-to-partner and partner-to-MAPK7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SAR1AP1 grouped by MAPK7-low versus MAPK7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAPK7→partner) and Y-score (partner→MAPK7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SAR1AP1 →	+0.144	+1.924	.001	<.001	3	4
LIHC	IMP3P2 →	+0.097	+3.765	<.001	.004	3	3
LIHC	OR13I1P →	+0.021	+3.429	.005	.009	3	2
CESC	RNU6-598P →	+0.394	+4.306	<.001	.001	3	2
CESC	RNA5SP198 →	+0.305	+5.144	<.001	<.001	3	2
CESC	RNU6-791P →	+0.155	+4.837	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,737 associations by consensus.

SAR1AP1 by MAPK7 expression — UCEC

Explore this box plot interactively →