MAPK4

Across TCGA patient cohorts, MAPK4 protein abundance is significantly associated with the RNA expression of many other genes, with 2,039 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MAPK4-associated genes across cancer lineages are RAD51, AKT2, and GTF2H1. Each is linked with MAPK4 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAPK4-to-partner and partner-to-MAPK4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAPK4 versus RAD51 in GBM, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAPK4→partner) and Y-score (partner→MAPK4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RAD51 →	-0.653	-0.528	<.001	<.001	3	2
OV	AKT2 →	+1.225	+1.629	.002	.004	3	1
OV	GTF2H1 →	-0.629	-1.719	.003	.009	3	1
OV	ACADS →	-1.320	-1.719	.004	.009	3	1
OV	RNF11 →	+0.929	+1.629	.003	.004	3	1
OV	HAT1 →	-0.646	-1.719	.009	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,039 associations by consensus.

MAPK4 vs RAD51 — GBM

Explore this scatter interactively →