MAPK4

Across TCGA cell cohorts, MAPK4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,262 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible MAPK4-associated GO terms across cancer lineages are Cytoplasmic translation, Regulation of syncytium formation by plasma membrane fusion, and Nuclear-transcribed mRNA catabolic process. Each is linked with MAPK4 in more than 9 cancer types. Because this analysis shows association rather than direction, both MAPK4-to-partner and partner-to-MAPK4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic translation grouped by MAPK4-low versus MAPK4-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAPK4→partner) and Y-score (partner→MAPK4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Cytoplasmic translation →	+0.104	+0.913	<.001	.003	3	9
STOMACH	Regulation of syncytium formation by plasma membrane fusion →	+0.112	+1.032	.001	.003	2	10
LUNG_NSCLC_LUSC	Nuclear-transcribed mRNA catabolic process →	+0.045	+0.065	.005	.008	3	9
STOMACH	Negative regulation of syncytium formation by plasma membrane fusion →	+0.126	+1.275	.001	<.001	3	8
STOMACH	Regulation of myoblast fusion →	+0.130	+0.890	<.001	.004	2	9
STOMACH	Negative regulation of myoblast fusion →	+0.148	+0.915	<.001	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,262 associations by consensus.

Cytoplasmic translation by MAPK4 expression — STOMACH

Explore this box plot interactively →