MAPK1IP1L

Across TCGA patient cohorts, MAPK1IP1L mutation is significantly associated with the RNA expression of many other genes, with 2,056 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAPK1IP1L-associated genes across cancer lineages are TRAJ21, ZMYND10-AS1, and MIR3925. Each is linked with MAPK1IP1L in more than 1 cancer types. Because this analysis shows association rather than direction, both MAPK1IP1L-to-partner and partner-to-MAPK1IP1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRAJ21 grouped by MAPK1IP1L-low versus MAPK1IP1L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAPK1IP1L→partner) and Y-score (partner→MAPK1IP1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TRAJ21 →	+0.391	+1.936	.001	.009	3	2
LUSC	ZMYND10-AS1 →	+0.156	+5.706	<.001	.003	3	2
LUSC	MIR3925 →	+0.472	+6.081	<.001	.002	3	2
UCEC	YTHDF3-AS1 →	+0.543	+3.354	.002	.005	3	1
UCEC	IGKV1OR2-118 →	+0.188	+1.965	.001	.002	3	1
UCEC	CCL5 →	+1.518	+2.684	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,056 associations by consensus.

TRAJ21 by MAPK1IP1L expression — UCEC

Explore this box plot interactively →