MAPK1IP1L

Across TCGA cell cohorts, MAPK1IP1L RNA expression is significantly associated with the go_rna of many other GO terms, with 3,744 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MAPK1IP1L-associated GO terms across cancer lineages are mRNA alternative polyadenylation, mRNA destabilization, and DNA-templated transcription initiation. Each is linked with MAPK1IP1L in more than 14 cancer types. Because this analysis shows association rather than direction, both MAPK1IP1L-to-partner and partner-to-MAPK1IP1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA alternative polyadenylation grouped by MAPK1IP1L-low versus MAPK1IP1L-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAPK1IP1L→partner) and Y-score (partner→MAPK1IP1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	mRNA alternative polyadenylation →	+0.077	+0.561	.001	.001	3	15
BLOOD_Lymphoma	mRNA destabilization →	+0.070	+0.939	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	DNA-templated transcription initiation →	+0.069	+0.751	.009	.002	3	13
PANCREAS	Positive regulation of DNA replication →	+0.085	+0.724	.005	.002	3	13
URINARY_TRACT	Regulation of cell cycle checkpoint →	+0.094	+1.089	.005	.001	3	12
BREAST	Positive regulation of cell cycle checkpoint →	+0.114	+0.692	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,744 associations by consensus.

mRNA alternative polyadenylation by MAPK1IP1L expression — BREAST

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