MAPK14

Across TCGA patient cohorts, MAPK14 protein abundance is significantly associated with the RNA expression of many other genes, with 18,415 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MAPK14-associated genes across cancer lineages are NCF2, TLR8, and PLEK. Each is linked with MAPK14 in more than 7 cancer types. Because this analysis shows association rather than direction, both MAPK14-to-partner and partner-to-MAPK14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAPK14 versus NCF2 in GBM, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAPK14→partner) and Y-score (partner→MAPK14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NCF2 →	+1.102	+0.328	<.001	<.001	3	8
OV	TLR8 →	+0.943	+0.218	<.001	<.001	3	7
COAD	PLEK →	+1.353	+0.213	<.001	<.001	3	7
OV	GPR65 →	+0.808	+0.228	<.001	<.001	3	7
GBM	ITGAX →	+0.903	+0.261	<.001	<.001	3	7
COAD	WAS →	+0.867	+0.201	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,415 associations by consensus.

MAPK14 vs NCF2 — GBM

Explore this scatter interactively →