Across TCGA cell cohorts, MAPK12 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,413 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MAPK12-associated GO terms across cancer lineages are Positive regulation of T-helper 17 cell lineage commitment, Positive regulation of muscle cell differentiation, and Calcium-independent cell-matrix adhesion. Each is linked with MAPK12 in more than 11 cancer types. Because this analysis shows association rather than direction, both MAPK12-to-partner and partner-to-MAPK12 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAPK12→partner) and Y-score (partner→MAPK12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of T-helper 17 cell lineage commitment →	+0.155	+1.088	.001	.003	3	12
BREAST	Positive regulation of muscle cell differentiation →	+0.166	+2.081	<.001	<.001	3	11
BONE	Calcium-independent cell-matrix adhesion →	+0.220	+1.283	<.001	<.001	3	11
URINARY_TRACT	XMP metabolic process →	+0.181	+2.435	<.001	<.001	3	11
URINARY_TRACT	XMP biosynthetic process →	+0.181	+2.435	<.001	<.001	3	11
URINARY_TRACT	'de novo' XMP biosynthetic process →	+0.181	+2.435	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,413 associations by consensus.

Exploration

MAPK12 survival (RNA) · tumor vs normal (RNA) · all MAPK12 data types