Across TCGA patient cohorts, MAPK11 protein abundance is significantly associated with the RNA expression of many other genes, with 5,274 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MAPK11-associated genes across cancer lineages are DAP3, RACK1, and CAV1. Each is linked with MAPK11 in more than 2 cancer types. Because this analysis shows association rather than direction, both MAPK11-to-partner and partner-to-MAPK11 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAPK11→partner) and Y-score (partner→MAPK11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DAP3 →	-0.436	-0.429	<.001	<.001	3	3
PDAC	RACK1 →	-0.440	-0.382	.007	.007	3	3
BRCA	CAV1 →	+1.496	+0.560	<.001	<.001	3	3
LSCC	MSTO1 →	-0.422	-0.353	.001	.004	3	3
LUAD	FLAD1 →	-0.395	-0.347	.004	<.001	3	3
LSCC	TSACC →	-0.533	-0.479	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,274 associations by consensus.

Exploration

MAPK11 survival (RNA) · tumor vs normal (RNA) · all MAPK11 data types