MAPK10

Across TCGA patient cohorts, MAPK10 protein abundance is significantly associated with the RNA expression of many other genes, with 9,637 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MAPK10-associated genes across cancer lineages are PLCXD3, SNHG3, and NRXN2. Each is linked with MAPK10 in more than 2 cancer types. Because this analysis shows association rather than direction, both MAPK10-to-partner and partner-to-MAPK10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAPK10 versus PLCXD3 in GBM, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAPK10→partner) and Y-score (partner→MAPK10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PLCXD3 →	+1.100	+0.431	<.001	<.001	3	3
CCRCC	SNHG3 →	-1.054	-1.036	<.001	.001	3	3
GBM	NRXN2 →	+0.846	+0.326	.003	.003	3	3
UCEC	PGAP4 →	+1.174	+0.803	.005	.002	3	3
UCEC	MAPK10-AS1 →	+0.985	+0.849	<.001	<.001	3	3
LSCC	GLI2 →	+1.274	+0.632	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,637 associations by consensus.

MAPK10 vs PLCXD3 — GBM

Explore this scatter interactively →