MAPK1

Across TCGA cell cohorts, MAPK1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,596 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MAPK1-associated GO terms across cancer lineages are Interleukin-34-mediated signaling pathway, Regulation of Golgi inheritance, and Positive regulation of macrophage proliferation. Each is linked with MAPK1 in more than 17 cancer types. Because this analysis shows association rather than direction, both MAPK1-to-partner and partner-to-MAPK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Interleukin-34-mediated signaling pathway grouped by MAPK1-low versus MAPK1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAPK1→partner) and Y-score (partner→MAPK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Interleukin-34-mediated signaling pathway →	+0.170	+1.558	<.001	<.001	3	18
KIDNEY	Regulation of Golgi inheritance →	+0.184	+1.530	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Positive regulation of macrophage proliferation →	+0.213	+1.165	<.001	<.001	3	17
BONE	Endosomal transport →	+0.082	+1.372	<.001	<.001	3	17
BONE	Cell division →	+0.066	+1.264	<.001	<.001	3	17
PANCREAS	Positive regulation of peptidyl-threonine phosphorylation →	+0.302	+1.275	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,596 associations by consensus.

Interleukin-34-mediated signaling pathway by MAPK1 expression — OESOPHAGUS

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