Across TCGA patient cohorts, MAP7D2 mutation is significantly associated with the total protein of many other genes, with 49 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAP7D2-associated genes across cancer lineages are ERK2, HER2_pY1248, and Annexin-1. Each is linked with MAP7D2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAP7D2-to-partner and partner-to-MAP7D2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP7D2→partner) and Y-score (partner→MAP7D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ERK2 →	+0.256	+2.247	<.001	.001	3	2
UCEC	HER2_pY1248 →	-0.164	-2.273	.042	<.001	3	2
UCEC	Annexin-1 →	+0.545	+2.415	<.001	.002	3	2
UCEC	Shc_pY317 →	-0.152	-1.584	<.001	.008	3	2
UCEC	14-3-3_beta →	-0.086	-1.308	.004	.012	3	1
UCEC	eEF2 →	+0.306	+1.321	.004	.012	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

Exploration

MAP7D2 survival (RNA) · tumor vs normal (RNA) · all MAP7D2 data types