MAP7D2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MAP7D2 mutation is significantly associated with the RNA expression of many other genes, with 35 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MAP7D2-associated genes across cancer lineages are REG3G, FAM25C, and COX4I2. Each is linked with MAP7D2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAP7D2-to-partner and partner-to-MAP7D2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP7D2→partner) and Y-score (partner→MAP7D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaREG3G →+0.026+4.867.004.00931
BLOOD_LymphomaFAM25C →+0.351+5.209<.001.00531
LUNG_NSCLC_LUADCOX4I2 →+0.055+4.228<.001<.00131
LUNG_NSCLC_LUADFABP12 →+0.118+3.215<.001.00731
LUNG_NSCLC_LUADWNT8A →+0.024+3.481<.001.00431
BLOOD_LeukemiaSLC32A1 →+0.818+4.223<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

Exploration