MAP7D1

Across TCGA cell cohorts, MAP7D1 mutation is significantly associated with the RNA expression of many other genes, with 751 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MAP7D1-associated genes across cancer lineages are PRMT9, SUPT20HL1, and BCL7A. Each is linked with MAP7D1 in more than 2 cancer types. Because this analysis shows association rather than direction, both MAP7D1-to-partner and partner-to-MAP7D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRMT9 grouped by MAP7D1-low versus MAP7D1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP7D1→partner) and Y-score (partner→MAP7D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PRMT9 →	+0.529	+2.628	.001	.002	3	3
OVARY	SUPT20HL1 →	+0.061	+3.807	.001	.009	3	2
LARGE_INTESTINE	BCL7A →	+0.726	+3.169	.003	.009	3	2
LARGE_INTESTINE	YWHAH →	+0.430	+2.628	.008	.002	3	2
LARGE_INTESTINE	TTI2 →	+0.566	+2.628	.003	.002	3	2
LARGE_INTESTINE	C12orf65 →	+0.469	+3.252	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 751 associations by consensus.

PRMT9 by MAP7D1 expression — LARGE_INTESTINE

Explore this box plot interactively →