MAP7

Across TCGA patient cohorts, MAP7 mutation is significantly associated with the RNA expression of many other genes, with 3,492 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAP7-associated genes across cancer lineages are GAGE2E, RNA5SP420, and RNA5SP45. Each is linked with MAP7 in more than 2 cancer types. Because this analysis shows association rather than direction, both MAP7-to-partner and partner-to-MAP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAGE2E grouped by MAP7-low versus MAP7-high in PRAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP7→partner) and Y-score (partner→MAP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PRAD	GAGE2E →	+0.094	+7.939	<.001	.008	3	3
UCEC	RNA5SP420 →	+0.461	+1.645	<.001	.008	3	3
PRAD	RNA5SP45 →	+0.343	+7.939	<.001	.008	3	2
PRAD	MIR4686 →	+0.838	+7.939	<.001	.008	3	2
SKCM	ZNF232-AS1 →	+0.481	+2.597	.003	.005	3	2
UCEC	RBAK-RBAKDN →	+0.078	+1.890	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,492 associations by consensus.

GAGE2E by MAP7 expression — PRAD

Explore this box plot interactively →