MAP7

Across TCGA cell cohorts, MAP7 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,138 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MAP7-associated GO terms across cancer lineages are Bundle of His cell to Purkinje myocyte communication, Regulation of endoplasmic reticulum unfolded protein response, and Basolateral protein secretion. Each is linked with MAP7 in more than 14 cancer types. Because this analysis shows association rather than direction, both MAP7-to-partner and partner-to-MAP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Bundle of His cell to Purkinje myocyte communication grouped by MAP7-low versus MAP7-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP7→partner) and Y-score (partner→MAP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Bundle of His cell to Purkinje myocyte communication →	+0.567	+1.003	.005	.001	2	15
OVARY	Regulation of endoplasmic reticulum unfolded protein response →	+0.060	+1.379	.002	.007	3	14
URINARY_TRACT	Basolateral protein secretion →	+0.250	+2.887	<.001	<.001	3	13
LUNG_SCLC	Desmosome assembly →	+0.442	+2.623	.007	<.001	3	13
PANCREAS	Negative regulation of Arp2/3 complex-mediated actin nucleation →	+0.207	+2.055	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Response to molecule of fungal origin →	+2.128	+3.094	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,138 associations by consensus.

Bundle of His cell to Purkinje myocyte communication by MAP7 expression — SKIN

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