MAP6D1

Across TCGA cell cohorts, MAP6D1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,952 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible MAP6D1-associated GO terms across cancer lineages are Pyrimidine-containing compound biosynthetic process, Cell cycle G1/S phase transition, and DNA strand elongation involved in DNA replication. Each is linked with MAP6D1 in more than 9 cancer types. Because this analysis shows association rather than direction, both MAP6D1-to-partner and partner-to-MAP6D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pyrimidine-containing compound biosynthetic process grouped by MAP6D1-low versus MAP6D1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP6D1→partner) and Y-score (partner→MAP6D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Pyrimidine-containing compound biosynthetic process →	+0.101	+0.900	<.001	.001	3	10
LARGE_INTESTINE	Cell cycle G1/S phase transition →	+0.056	+0.954	<.001	<.001	3	10
SOFT_TISSUE	DNA strand elongation involved in DNA replication →	+0.173	+1.163	.001	<.001	3	9
URINARY_TRACT	Transcription initiation at RNA polymerase II promoter →	+0.048	+1.110	.003	.005	3	9
BONE	G1/S transition of mitotic cell cycle →	+0.059	+0.726	.008	<.001	2	10
STOMACH	Positive regulation of mitotic cell cycle phase transition →	+0.099	+0.894	.008	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,952 associations by consensus.

Pyrimidine-containing compound biosynthetic process by MAP6D1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →