MAP4K2

Across TCGA patient cohorts, MAP4K2 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,587 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible MAP4K2-associated proteins across cancer lineages are MAP4K2_S328, MAP4K2_S394, and MYDGF. Each is linked with MAP4K2 in more than 6 cancer types. Because this analysis shows association rather than direction, both MAP4K2-to-partner and partner-to-MAP4K2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAP4K2 versus MAP4K2_S328 in OV, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP4K2→partner) and Y-score (partner→MAP4K2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MAP4K2_S328 →	+0.652	+0.656	<.001	.001	3	7
LUAD	MAP4K2_S394 →	+0.399	+0.420	<.001	<.001	3	6
CCRCC	MYDGF →	-0.428	-0.414	<.001	<.001	3	3
LSCC	NELFB →	+0.316	+0.594	<.001	<.001	3	3
LUAD	NSUN2 →	+0.368	+0.441	<.001	.001	3	3
OV	ARHGAP26 →	-0.453	-0.428	.001	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,587 associations by consensus.

MAP4K2 vs MAP4K2_S328 — OV

Explore this scatter interactively →