MAP4K1

Across TCGA patient cohorts, MAP4K1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,766 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MAP4K1-associated proteins across cancer lineages are RAC2, ADA2, and CD4. Each is linked with MAP4K1 in more than 9 cancer types. Because this analysis shows association rather than direction, both MAP4K1-to-partner and partner-to-MAP4K1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAP4K1 versus RAC2 in BRCA, with a Pearson correlation of 0.70.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP4K1→partner) and Y-score (partner→MAP4K1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RAC2 →	+0.889	+1.003	<.001	<.001	3	10
HNSC	ADA2 →	+0.603	+1.201	<.001	<.001	3	10
HNSC	CD4 →	+0.689	+0.976	<.001	<.001	3	10
HNSC	CD48 →	+0.885	+0.850	<.001	<.001	3	10
HNSC	COTL1 →	+0.573	+0.949	<.001	<.001	3	10
HNSC	DOCK2 →	+0.665	+1.234	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,766 associations by consensus.

MAP4K1 vs RAC2 — BRCA

Explore this scatter interactively →