MAP4

Across TCGA pan-cancer cohorts, MAP4 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated MAP4 data layer compared with 25 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher MAP4 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated MAP4 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

UCEC, LSCC, and GBM are the cancer types where MAP4 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	All	0.829	0.985	.003	28	view →
LSCC	OS	Quartile	II,III,IV	0.698	0.964	.011	13	view →
GBM	DFS	Median	All	0.607	0.813	.005	7	view →
PDAC	DFS	Median	IV	0.250	0.934	.024	4	view →
HNSC	DFS	Tertile	III,IV	1.000	0.908	.042	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

MAP4–UCEC (OS)

Open the UCEC breakdown →