MAP4

Across TCGA cell cohorts, MAP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,397 significant associations in total. CNS shows the largest number of these associations.

The most reproducible MAP4-associated GO terms across cancer lineages are Protein depolymerization, Chemokine (C-C motif) ligand 21 signaling pathway, and Positive regulation of establishment of T cell polarity. Each is linked with MAP4 in more than 15 cancer types. Because this analysis shows association rather than direction, both MAP4-to-partner and partner-to-MAP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein depolymerization grouped by MAP4-low versus MAP4-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP4→partner) and Y-score (partner→MAP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Protein depolymerization →	+0.116	+0.836	<.001	<.001	3	16
URINARY_TRACT	Chemokine (C-C motif) ligand 21 signaling pathway →	+0.185	+1.143	<.001	<.001	3	16
LIVER	Positive regulation of establishment of T cell polarity →	+0.241	+0.930	<.001	<.001	3	15
LARGE_INTESTINE	Positive regulation of early endosome to late endosome transport →	+0.142	+0.624	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Actin filament depolymerization →	+0.215	+1.156	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Negative regulation of Rho protein signal transduction →	+0.229	+1.324	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,397 associations by consensus.

Protein depolymerization by MAP4 expression — SKIN

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