MAP3K9

Across TCGA cell cohorts, MAP3K9 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,402 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MAP3K9-associated GO terms across cancer lineages are Regulation of protein localization to nucleus, Positive regulation of nucleocytoplasmic transport, and Post-transcriptional gene silencing. Each is linked with MAP3K9 in more than 13 cancer types. Because this analysis shows association rather than direction, both MAP3K9-to-partner and partner-to-MAP3K9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein localization to nucleus grouped by MAP3K9-low versus MAP3K9-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP3K9→partner) and Y-score (partner→MAP3K9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of protein localization to nucleus →	+0.093	+1.154	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Positive regulation of nucleocytoplasmic transport →	+0.079	+1.209	.006	<.001	3	13
OESOPHAGUS	Post-transcriptional gene silencing →	+0.101	+0.914	<.001	<.001	3	13
BLOOD_Lymphoma	Negative regulation of chromosome condensation →	+0.145	+1.000	<.001	<.001	3	13
STOMACH	Regulatory ncRNA-mediated gene silencing →	+0.084	+1.348	<.001	<.001	3	13
STOMACH	miRNA processing →	+0.092	+0.995	<.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,402 associations by consensus.

Regulation of protein localization to nucleus by MAP3K9 expression — OVARY

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