MAP3K7

Across TCGA patient cohorts, MAP3K7 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,875 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MAP3K7-associated proteins across cancer lineages are SYNCRIP, PGM3, and SMAP1. Each is linked with MAP3K7 in more than 5 cancer types. Because this analysis shows association rather than direction, both MAP3K7-to-partner and partner-to-MAP3K7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAP3K7 versus SYNCRIP in GBM, with a Pearson correlation of 0.53.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP3K7→partner) and Y-score (partner→MAP3K7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SYNCRIP →	+0.346	+0.405	<.001	<.001	3	6
BRCA	PGM3 →	+0.356	+0.621	<.001	<.001	3	5
GBM	SMAP1 →	+0.316	+0.404	<.001	<.001	3	5
HNSC	HDAC2 →	+0.373	+0.760	<.001	.006	3	5
OV	PCBD2 →	-0.427	-0.530	.006	.002	2	5
BRCA	RNGTT →	+0.363	+0.476	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,875 associations by consensus.

MAP3K7 vs SYNCRIP — GBM

Explore this scatter interactively →