MAP3K7

Across TCGA patient cohorts, MAP3K7 protein abundance is significantly associated with the RNA expression of many other genes, with 14,235 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MAP3K7-associated genes across cancer lineages are TAB2, DCBLD2, and GSDME. Each is linked with MAP3K7 in more than 5 cancer types. Because this analysis shows association rather than direction, both MAP3K7-to-partner and partner-to-MAP3K7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAP3K7 versus TAB2 in BRCA, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP3K7→partner) and Y-score (partner→MAP3K7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TAB2 →	+0.644	+0.170	<.001	<.001	3	6
PDAC	DCBLD2 →	+0.907	+0.147	<.001	<.001	3	5
COAD	GSDME →	+0.671	+0.175	<.001	<.001	3	4
UCEC	PDLIM7 →	+0.629	+0.155	.001	.003	3	4
LSCC	TACC2 →	-0.718	-0.115	<.001	<.001	3	4
LSCC	BDH1 →	-0.853	-0.120	.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,235 associations by consensus.

MAP3K7 vs TAB2 — BRCA

Explore this scatter interactively →