MAP3K7

Across TCGA cell cohorts, MAP3K7 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,747 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MAP3K7-associated GO terms across cancer lineages are Import into nucleus, Termination of RNA polymerase II transcription, and Protein import into nucleus. Each is linked with MAP3K7 in more than 16 cancer types. Because this analysis shows association rather than direction, both MAP3K7-to-partner and partner-to-MAP3K7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Import into nucleus grouped by MAP3K7-low versus MAP3K7-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP3K7→partner) and Y-score (partner→MAP3K7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Import into nucleus →	+0.054	+0.673	<.001	<.001	3	17
LUNG_SCLC	Termination of RNA polymerase II transcription →	+0.161	+0.576	<.001	.001	3	17
STOMACH	Protein import into nucleus →	+0.096	+1.126	<.001	<.001	3	17
LUNG_NSCLC_LUSC	Regulation of metaphase/anaphase transition of cell cycle →	+0.119	+0.941	.002	.003	3	17
LUNG_NSCLC_LUSC	Regulation of mitotic metaphase/anaphase transition →	+0.125	+1.027	.002	<.001	3	17
STOMACH	Nuclear transport →	+0.089	+1.009	<.001	.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,747 associations by consensus.

Import into nucleus by MAP3K7 expression — STOMACH

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