MAP3K6

Across TCGA patient cohorts, MAP3K6 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,946 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MAP3K6-associated proteins across cancer lineages are NDUFAF4, MIEN1, and NIBAN2. Each is linked with MAP3K6 in more than 4 cancer types. Because this analysis shows association rather than direction, both MAP3K6-to-partner and partner-to-MAP3K6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAP3K6 versus NDUFAF4 in OV, with a Pearson correlation of -0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP3K6→partner) and Y-score (partner→MAP3K6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	NDUFAF4 →	-0.461	-0.796	<.001	<.001	3	5
BRCA	MIEN1 →	-1.106	-1.023	<.001	<.001	3	4
GBM	NIBAN2 →	+0.443	+0.515	<.001	.002	3	4
OV	PLOD1 →	+0.596	+0.838	<.001	.003	3	4
CCRCC	PYGL →	+0.567	+0.559	<.001	.003	3	4
BRCA	HID1 →	-0.569	-0.794	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,946 associations by consensus.

MAP3K6 vs NDUFAF4 — OV

Explore this scatter interactively →