Across TCGA patient cohorts, MAP3K5 protein abundance is significantly associated with the RNA expression of many other genes, with 11,475 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MAP3K5-associated genes across cancer lineages are RNA5SP219, MAP3K5-AS1, and MIR223HG. Each is linked with MAP3K5 in more than 7 cancer types. Because this analysis shows association rather than direction, both MAP3K5-to-partner and partner-to-MAP3K5 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP3K5→partner) and Y-score (partner→MAP3K5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP219 →	+1.095	+0.370	<.001	<.001	3	8
UCEC	MAP3K5-AS1 →	+0.910	+0.515	<.001	<.001	3	8
HNSC	MIR223HG →	+0.924	+0.234	<.001	.007	3	6
COAD	RAE1 →	-1.011	-0.360	<.001	.001	3	5
LSCC	CORO1A →	+0.624	+0.216	<.001	<.001	3	5
COAD	PRDM8 →	+0.908	+0.380	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,475 associations by consensus.

Exploration

MAP3K5 survival (RNA) · tumor vs normal (RNA) · all MAP3K5 data types