Across TCGA cell cohorts, MAP3K3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,226 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MAP3K3-associated GO terms across cancer lineages are Negative regulation of cilium assembly, Regulation of cytokinetic process, and Regulation of mitotic cytokinetic process. Each is linked with MAP3K3 in more than 15 cancer types. Because this analysis shows association rather than direction, both MAP3K3-to-partner and partner-to-MAP3K3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP3K3→partner) and Y-score (partner→MAP3K3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Negative regulation of cilium assembly →	+0.086	+1.204	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Regulation of cytokinetic process →	+0.138	+0.970	<.001	.001	3	15
UPPER_AERODIGESTIVE_TRACT	Regulation of mitotic cytokinetic process →	+0.138	+0.970	<.001	.001	3	15
UPPER_AERODIGESTIVE_TRACT	Positive regulation of mitotic cytokinetic process →	+0.138	+0.970	<.001	.001	3	15
LUNG_NSCLC_LUSC	Cell division →	+0.079	+1.404	.002	.005	3	14
LUNG_SCLC	Subtelomeric heterochromatin formation →	+0.121	+0.557	.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,226 associations by consensus.

Exploration

MAP3K3 survival (RNA) · tumor vs normal (RNA) · all MAP3K3 data types