MAP3K20-AS1

Across TCGA pan-cancer cohorts, MAP3K20-AS1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of MAP3K20-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where MAP3K20-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MAP3K20-AS1 is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.

HNSC, COAD, and KIRC are the cancer types where MAP3K20-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MAP3K20-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	II,III,IV	+0.475	<.001	10	view →
COAD	All	All	+0.912	<.001	9	view →
KIRC	Male	II,III,IV	+0.178	<.001	9	view →
THCA	Male	III,IV	+0.150	.013	7	view →
KIRP	All	All	+0.200	<.001	6	view →
LIHC	All	II,III,IV	+0.117	.029	3	view →
CHOL	All	All	+1.084	.017	2	view →
STAD	All	All	+0.763	.034	2	view →
KICH	All	All	+0.191	.017	2	view →
BRCA	All	All	+0.103	.039	2	view →
LUSC	Female	II,III,IV	−0.188	.035	1	view →
LUAD	All	All	+0.188	.021	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

MAP3K20-AS1–HNSC

Open the HNSC breakdown →