MAP3K2

Across TCGA patient cohorts, MAP3K2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,723 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible MAP3K2-associated proteins across cancer lineages are RAB3D, MRPS25, and RPL4. Each is linked with MAP3K2 in more than 4 cancer types. Because this analysis shows association rather than direction, both MAP3K2-to-partner and partner-to-MAP3K2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAP3K2 versus RAB3D in HNSC, with a Pearson correlation of -0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP3K2→partner) and Y-score (partner→MAP3K2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RAB3D →	-0.613	-0.659	<.001	<.001	3	5
OV	MRPS25 →	-0.455	-0.760	<.001	<.001	3	5
BRCA	RPL4 →	-0.396	-0.613	<.001	<.001	3	4
BRCA	RPL6 →	-0.406	-0.445	<.001	.001	3	4
BRCA	MTERF4 →	-0.463	-0.423	<.001	.004	2	5
OV	PPIF →	-0.662	-0.800	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,723 associations by consensus.

MAP3K2 vs RAB3D — HNSC

Explore this scatter interactively →