MAP3K2

Across TCGA patient cohorts, MAP3K2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,367 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible MAP3K2-associated genes across cancer lineages are FN1, ANTXR2, and RAC2. Each is linked with MAP3K2 in more than 5 cancer types. Because this analysis shows association rather than direction, both MAP3K2-to-partner and partner-to-MAP3K2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAP3K2 versus FN1 in OV, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP3K2→partner) and Y-score (partner→MAP3K2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FN1 →	+2.265	+0.281	<.001	<.001	3	5
LSCC	ANTXR2 →	+0.773	+0.197	<.001	<.001	3	5
GBM	RAC2 →	+1.095	+0.343	<.001	<.001	3	5
GBM	CD109 →	+1.055	+0.274	<.001	.005	3	5
OV	PLAUR →	+0.951	+0.245	<.001	<.001	3	4
OV	FHL2 →	+0.843	+0.276	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,367 associations by consensus.

MAP3K2 vs FN1 — OV

Explore this scatter interactively →