MAP3K19

Across TCGA patient cohorts, MAP3K19 mutation is significantly associated with the RNA expression of many other genes, with 4,807 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAP3K19-associated genes across cancer lineages are LINC01892, RFC5, and DCLRE1B. Each is linked with MAP3K19 in more than 3 cancer types. Because this analysis shows association rather than direction, both MAP3K19-to-partner and partner-to-MAP3K19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01892 grouped by MAP3K19-low versus MAP3K19-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP3K19→partner) and Y-score (partner→MAP3K19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	LINC01892 →	+0.024	+4.122	.001	.008	3	4
UCEC	RFC5 →	+0.527	+1.847	<.001	<.001	3	4
UCEC	DCLRE1B →	+0.579	+1.771	<.001	<.001	3	4
UCEC	KNSTRN →	+0.534	+2.600	<.001	<.001	3	4
HNSC	MIR6781 →	+0.351	+2.045	.005	.006	3	4
UCEC	ERG →	-0.341	-1.418	.006	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,807 associations by consensus.

LINC01892 by MAP3K19 expression — BLCA

Explore this box plot interactively →